Polly J Ferguson Selected Research

Chronic recurrent multifocal osteomyelitis

1/2020	Imaging mimics of chronic recurrent multifocal osteomyelitis: avoiding pitfalls in a diagnosis of exclusion.
11/2019	Gain-of-function mutations in a member of the Src family kinases cause autoinflammatory bone disease in mice and humans.
12/2017	Chronic Recurrent Multifocal Osteomyelitis (CRMO): Presentation, Pathogenesis, and Treatment.
4/2017	Chronic Recurrent Multifocal Osteomyelitis and Related Diseases-Update on Pathogenesis.
7/2015	New discoveries in CRMO: IL-1β, the neutrophil, and the microbiome implicated in disease pathogenesis in Pstpip2-deficient mice.
1/2014	Inflammasome-independent IL-1β mediates autoinflammatory disease in Pstpip2-deficient mice.
9/2013	Autoinflammatory bone disorders: update on immunologic abnormalities and clues about possible triggers.
4/2012	Current understanding of the pathogenesis and management of chronic recurrent multifocal osteomyelitis.

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Polly J Ferguson Research Topics

Disease

8	Majeed syndrome 01/2021 - 12/2011
8	Chronic recurrent multifocal osteomyelitis 01/2020 - 04/2012
6	Osteomyelitis 01/2021 - 12/2011
6	Inflammation (Inflammations) 01/2020 - 06/2009
4	Traumatic Brain Injuries (Traumatic Brain Injury) 07/2021 - 03/2018
4	Uveitis 01/2021 - 01/2018
4	Osteitis 11/2013 - 12/2011
3	Bone Diseases (Bone Disease) 11/2019 - 03/2013
3	Arthritis (Polyarthritis) 01/2019 - 10/2009
2	Juvenile Arthritis (Juvenile Idiopathic Arthritis) 01/2022 - 01/2022
2	Cryopyrin-Associated Periodic Syndromes 01/2021 - 12/2011
2	Localized Scleroderma (Morphea) 01/2020 - 07/2019
2	Sacroiliitis 01/2019 - 01/2019
2	Infections 02/2015 - 06/2009
1	Fever (Fevers) 11/2020
1	COVID-19 11/2020
1	Autoimmune Hemolytic Anemia (Cold Agglutinin Disease) 07/2019
1	Cytopenia 07/2019
1	Neutropenia 07/2019
1	Idiopathic Thrombocytopenic Purpura (Thrombocytopenic Purpura, Autoimmune) 07/2019
1	Evans Syndrome 07/2019
1	Fibrosis (Cirrhosis) 01/2018
1	Retinal Degeneration 01/2018
1	Eye Diseases (Eye Disease) 01/2018
1	Hearing Loss (Hearing Impairment) 01/2018
1	Septic Shock (Toxic Shock Syndrome) 02/2016
1	Sepsis (Septicemia) 02/2016
1	Seizures (Absence Seizure) 03/2015
1	Lyme Disease (Disease, Lyme) 05/2014
1	Pyogenic arthritis, pyoderma gangrenosum, and acne 04/2014
1	Disease Progression 01/2014
1	Cherubism 11/2013
1	Hyperostosis 11/2013
1	Acne Vulgaris 11/2013
1	Synovitis 11/2013
1	Acquired Hyperostosis Syndrome (SAPHO Syndrome) 09/2013
1	Dandy-Walker Syndrome (Dandy Walker Malformation) 08/2013
1	Encephalocele (Encephalocele, Frontal) 08/2013
1	Necrosis 03/2013
1	Autism Spectrum Disorder 01/2013
1	Dermatitis 12/2011
1	Psoriasis (Pustulosis Palmaris et Plantaris) 12/2011
1	Xanthomatosis (Xanthoma) 10/2009
1	Vasculitis (Vasculitides) 03/2005

Drug/Important Bio-Agent (IBA)

11	Interleukin-1 (Interleukin 1)IBA 01/2021 - 06/2009
5	CytokinesIBA 01/2020 - 04/2012
4	Proteins (Proteins, Gene)FDA Link 01/2021 - 08/2013
4	AutoantibodiesIBA 01/2020 - 06/2009
4	Methotrexate (Mexate)FDA LinkGeneric 01/2020 - 05/2014
4	InflammasomesIBA 01/2018 - 01/2014
3	Interleukin-1 Receptors (Interleukin 1 Receptor)IBA 01/2021 - 04/2012
3	Tumor Necrosis Factor InhibitorsIBA 01/2019 - 03/2013
3	Biological ProductsIBA 01/2019 - 03/2013
2	Acute-Phase Proteins (Acute-Phase Protein)IBA 01/2021 - 12/2011
2	src-Family KinasesIBA 01/2021 - 11/2019
2	Biomarkers (Surrogate Marker)IBA 12/2020 - 12/2017
2	Adalimumab (Humira)FDA Link 01/2019 - 01/2019
2	Monoclonal AntibodiesIBA 01/2019 - 01/2019
2	GlucocorticoidsIBA 01/2019 - 01/2019
2	Infliximab (Remicade)FDA Link 01/2019 - 01/2019
2	Adrenal Cortex Hormones (Corticosteroids)IBA 03/2013 - 12/2011
1	Interferon Type IIBA 07/2021
1	Caspase 1 (ICE Protease)IBA 01/2021
1	Macrophage Inflammatory Proteins (Macrophage Inflammatory Protein 1)IBA 01/2021
1	LipopolysaccharidesIBA 01/2021
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2021
1	collagen type I trimeric cross-linked peptideIBA 12/2020
1	Diphosphonates (Bisphosphonates)IBA 12/2020
1	Cytidine Triphosphate (CTP)IBA 01/2020
1	Retinaldehyde (Retinal)IBA 01/2020
1	Phosphotransferases (Kinase)IBA 11/2019
1	Mutant Proteins (Protein, Mutant)IBA 11/2019
1	Rituximab (Mabthera)FDA Link 07/2019
1	Intravenous Immunoglobulins (IVIG)FDA Link 07/2019
1	SteroidsIBA 07/2019
1	Peptide Hydrolases (Proteases)FDA Link 01/2018
1	Purinergic P2X7 ReceptorsIBA 01/2018
1	CalpainIBA 01/2018
1	LipidsIBA 04/2017
1	Caspase 8 (Caspase-8)IBA 07/2015
1	Ubiquitin-Specific ProteasesIBA 03/2015
1	ubiquitin isopeptidaseIBA 03/2015
1	Antinuclear AntibodiesIBA 05/2014
1	Serine Proteases (Serine Protease)IBA 01/2014
1	Proline (L-Proline)FDA Link 01/2014
1	Phosphoprotein Phosphatases (Phosphatases, Protein)IBA 01/2014
1	Deficiency of interleukin-1 receptor antagonistIBA 11/2013
1	Etanercept (Enbrel)FDA Link 03/2013
1	Synapsins (Synapsin I)IBA 01/2013
1	Acitretin FDA Link 12/2011
1	AntigensIBA 12/2011
1	Antineutrophil Cytoplasmic Antibodies (ANCA)IBA 03/2005

Therapy/Procedure

10	Therapeutics 01/2022 - 10/2009
2	Critical Care (Surgical Intensive Care) 11/2020 - 02/2016
1	Braces 01/2020
1	Cell Transplantation 07/2019
1	Length of Stay 02/2016
1	Biological Therapy 03/2013